Quantitative structure-activity relationship (QSAR) is an important drug design approach to understand the relationship between the chemical structure and their biological activity. The book describes brief introduction to hepatitis C virus (HCV), life cycle, identified targets and current progress towards development of anti-HCV agents. 2D and 3D-QSAR studies for anti-HCV compounds from different categories targeting NS5B polymerase have been incorporated. Some of the selected categories are nucleoside and non-nucleosides.
Vaishali M Patil
Dr. Vaishali M. Patil has academic and industry experience of 15 years. Her research interests are synthetic chemistry, computational chemistry, QSAR and their application for drug discovery. She has excellent research publications and some reviews to her credit in esteemed journals and few chapters in Elsevier, Nova, and Springer published books.
Satya Prakash Gupta
Number of Pages:
LAP LAMBERT Academic Publishing
Hepatitis C virus, NS5B Polymerase, HCV Inhibitors, QSAR
SCIENCE / Chemistry / Physical & Theoretical