978-3-330-08402-5

Hepatitis C Virus: QSAR Studies on Polymerase Inhibitors

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Summary:

Quantitative structure-activity relationship (QSAR) is an important drug design approach to understand the relationship between the chemical structure and their biological activity. The book describes brief introduction to hepatitis C virus (HCV), life cycle, identified targets and current progress towards development of anti-HCV agents. 2D and 3D-QSAR studies for anti-HCV compounds from different categories targeting NS5B polymerase have been incorporated. Some of the selected categories are nucleoside and non-nucleosides.

Author:

Vaishali M Patil

Biographie:

Dr. Vaishali M. Patil has academic and industry experience of 15 years. Her research interests are synthetic chemistry, computational chemistry, QSAR and their application for drug discovery. She has excellent research publications and some reviews to her credit in esteemed journals and few chapters in Elsevier, Nova, and Springer published books.

Author:

Satya Prakash Gupta

Biographie:

Author:

Neeraj Masand

Biographie:

Number of Pages:

88

Book language:

English

Published On:

2019-01-04

ISBN:

978-3-330-08402-5

Publishing House:

LAP LAMBERT Academic Publishing

Keywords:

Hepatitis C virus, NS5B Polymerase, HCV Inhibitors, QSAR

Product category:

SCIENCE / Chemistry / Physical & Theoretical