978-3-659-97244-7

Preparation Of Isoxazole Derivatives

Preparation of 2-(benzo[4,5]thieno[3,2-d]isoxazol-3-yloxy)-N-(aryl)acetamide and other derivatives.

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Summary:

Medicinal chemistry is a scientific discipline of chemistry and pharmacology. Isoxazole is an azole with an oxygen atom next to the nitrogen. It is also the class of compounds containing this ring. Isoxazolyl is the univalent radical derived from isoxazole. Isoxazole rings are found in some natural products, such as ibotenic acid and muscimol. Isoxazoles also form the basis for a number of drugs, including the COX-2 inhibitor valdecoxib and a neurotransmitter agonist AMPA. An isoxazolyl group is found in many beta-lactamase-resistant antibiotics, such as cloxacillin, dicloxacillin and flucloxacillin. Leflunomide is an isoxazole-derivative.The work on new isoxasole derivatives are establish how a substance operates in the body and its suitability for use as a drugs.

Author:

S. A. Joshi

Biographie:

Dr.S.A.Joshi working as assistant professor in M.N.Science College, Visnagar. Other two author Dr.K.V.Goswami working as assistant professor in The H.N.S.B.Ltd Science College, Himatnaga, and Dr.Rinku.P.Patel working in Bhavans Science College, Dakor.

Author:

K. V. Goswami

Biographie:

Author:

R.P. Patel

Biographie:

Number of Pages:

92

Book language:

English

Published On:

2018-09-17

ISBN:

978-3-659-97244-7

Publishing House:

LAP LAMBERT Academic Publishing

Keywords:

Isoxazole, preparation, derivatives, Acetamide, Spectroscopic Analysis, Biological evolution

Product category:

SCIENCE / Chemistry / Organic