Vitamins play an important role in human health and therefore, the bioavailability and delivery of these micronutrients in solution have been the subject of intensive investigations. In this book, we monitor the delivery of vitamin A (retinol and retinoic acid), vitamin B (folic acid) and vitamin C (L-ascorbic acid) by serum proteins such as human serum albumin (HSA), bovine serum albumin (BSA) and beta-lactoglobulin (b-LG). The loading efficacy of these vitamins with serum proteins are studied in solution. Vitamins bind serum proteins via hydrophilic, hydrophobic and H-bonding contacts. The loading efficacies of these vitamins were from 40% to 60%. Serum proteins are capable of delivery of these micronutrients in vitro and in vivo.
Heidar Ali Tajmir Riahi
Heidar-Ali Tajmir-Riahi: Research Professor at University of Quebec in Trois-Rivieres (UQTR), Canada. He was admitted to the Circle of Excellence of Quebec University in 2017. He has 350 publications in international journals with 9 books and 15 book chapters. Research interest: drug interactions with DNA, RNA and proteins; drug delivery.
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Éditions universitaires européennes
serum proteins, vitamin A, vitamin B, vitamin C, delivery of vitamins
SCIENCE / Biochemistry