978-620-0-25179-4

A Common Pathway Drug Design for all types of Cardiovascular Diseases

A Network Biology Approach

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Summary:

Cardiovascular diseases are becoming a key concern globally over an era across all non-communicable diseases. Cardiovascular diseases have been occurring around the world due to some widespread risk variables. Diseases have such a genetic association emerging from equivalent risk factors, either indirectly or directly. If a gene loses its normal activity and adversely affects the body a disease is caused. Currently, it is observed that the inability of a disease through the protein-protein interaction is more fruitful than the single gene. Multiple scientific studies have uncovered tactics to use advanced Bioinformatics strategies and tools in network biology to construct a structure-based drug from crucial biomolecule or protein for diseases. This study determines the protein-protein interaction network and designs a common pathway drug for all types of cardiovascular diseases. The data mining application called knowledge discovery in database has been performed and genes are filtered, pre-processed, converted and mined to locate common genes for all types of cardiovascular diseases. To accomplish the goal, Unihi is used as a tool.

Author:

Al - Mustanjid

Biographie:

Al - Mustanjid was born in Bangladesh and he is an expert in Network Biology. He has research interest in Bioinformatics, Software Development Life Cycle (SDLC), Data Mining and Statistical Analysis.

Author:

Md. Habibur Rahman

Biographie:

Author:

Chandan Mandal

Biographie:

Number of Pages:

56

Book language:

English

Published On:

2019-07-25

ISBN:

978-620-0-25179-4

Publishing House:

LAP LAMBERT Academic Publishing

Keywords:

cardiovascular diseases, R, Data Mining, Protein-protein interaction, Drug design, UniHi

Product category:

COMPUTERS / General