978-620-2-67224-5

Formulation and Evaluation of Controlled Release Mucoadhesive Tablets

An approach to formulate, optimize and evaluate controlled release mucoadhesive tablets using synergy gum blends

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Summary:

An ideal dosage form is one, which attains the desired therapeutic concentration of drug in plasma and maintains constant for entire duration of treatment. This is possible through administration of a conventional dosage form in a particular dose and at particular frequency. In most cases, the dosing interval much shorter than the half life of the drug resulting in a number of limitations associated with such a conventional dosage form. It is evident from the recent scientific and patent literature that an increased interest in novel dosage forms that are retained in stomach for a prolonged and predictable period of time exists today in academic and industrial research groups. One of the most feasible approaches for achieving a prolonged and predictable drug delivery profile in the GI tract is to control the gastric residence time, i.e. Gastro retentive Dosage Forms, which will provide us with new and important therapeutic options. These efforts results in Gastro retentive dosage forms that was designed in large part based on different approaches and one of which is Mucoadhesive drug delivery system using bioadhesive polymer to enable it to adhere mucous wall of stomach.

Author:

Vilas Nilkanthrao Deshmukh

Biographie:

Dr. Vilas Nilkanthrao Deshmukh has completed his PhD. in Pharmaceutical Sciences from Sant Gadge Baba Amravati University, Amravati, Maharashtra, India. He has 20 years of teaching experience at B.Pharm and M.Pharm level and guiding four students for PhD. research work. He has several publications in National and International Journals.

Number of Pages:

76

Book language:

English

Published On:

2020-07-07

ISBN:

978-620-2-67224-5

Publishing House:

LAP LAMBERT Academic Publishing

Keywords:

Mucoadhesive tablet, Controlled release, formulation, evaluation, Hydrophilic gums

Product category:

MEDICAL / Pharmacology